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The weekend sees the initial Wear-Tyne derby since 2024, but which side will celebrate – Sunderland or Newcastle?
"During the bulk of last season, you couldn't have imagined the Wearside club earning promotion and challenging with Eddie Howe's Newcastle, never mind being above them in the table," stated football expert Chris Sutton.
"Things are very different now, and the way Sunderland play leads me to believe they've got a genuine opportunity."
The analyst is providing predictions for all 380 Premier League games this campaign, in competition with AI, fans and a range of guests.
For week 16, he takes on England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the eLions – the Football Association's recognised esports team – at the gaming title European esports championship finals tournament, which is being held at Twickenham Stadium on Saturday.
You can watch Uefa's video platform, Instagram Live and TikTok channels, as well as EA Sports FC Twitch and its YouTube counterpart and the national team's Twitch.
Do you agree with their predictions? You can make your own projections below.
The most commonly selected scoreline chosen for each game is used in the leaderboards at the bottom of this page.
Getting the win/draw/loss right (picking a win, draw or defeat) is worth 10 points. The exact score earns 40 points.
Ray, who also plays his club side and the Premier League champions as well as England, is making his debut at the eEuros finals after getting through the qualification rounds.
Eight players will fly the flag at the finals in a single-elimination, playing for a substantial cash prize and a coveted spot in the world finals play-offs, with the Danish representative Anders Vejrgang defending the title he won last year.
"I'm feeling really good for it," Ray said. "There's a really good coach alongside me and training has been going well.
"It is invariably an honour to play for your country. Naturally when you are younger, you dream about doing it as an professional footballer, but when you pursue a career in this profession and there is an chance to represent England, wearing the Three Lions is something unique.
"I overcame Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"For me he is the best player in the world so beating him in a tournament like this just delivers a crazy boost of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The Blues were outstanding against Arsenal at the end of November, when they secured a point after going down to 10 men, and many thought they've turned a corner, they could potentially be challengers for the crown.
However, since that game, however, they were overpowered by Leeds, looked flat against Bournemouth and this week got defeated by Atalanta in the Champions League.
So head coach Enzo Maresca really needs a win here to get back on track, but it won't be easy because the Toffees are such a threatening team.
Their key midfielders are playing really well and Everton have got a bit of a positive run at the moment.
Current evidence suggests you would probably back Everton, while the most prudent prediction would probably be a draw, but I'm throwing caution to the wind.
Chelsea haven't given me any real reason to back them recently, but I just have a gut instinct Chelsea will emerge victorious because they are at home and they are in need of three points.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I am at this game and it will be fascinating to see what we get from Liverpool.
I was delighted for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday after all the controversy with Mohamed Salah this week.
Slot should not have to put up with that drama. I know Salah has been a great for Liverpool but fundamentally Slot just wants to win games and there is no ulterior motive in his team selection.
Liverpool changed their shape against Inter and went with a midfield diamond and two up top.
All the talk is going to be talking about whether Salah is included for this game, but the only way he is going to be brought back into the fold is if he says sorry.
Slot's focus will be on winning this game, but it is a challenging encounter.
You could argue it is the same for most teams but I find Brighton so hard to predict. I always feel they have got a goal in them, but they are vulnerable at the back too.
Liverpool need to get back to winning consistently, but I am not sure how much their efforts at the San Siro will have affected their stamina.
I've selected a couple of Brighton players in my Fantasy Premier League side, so they will likely do poorly - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the opportunity to rest while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to be pegged back late on.
With the exception of their excellent performance against Everton a couple of weeks ago, Newcastle's away form has been poor, especially straight after they've played in the Champions League.
It is anticipated that that trend to continue on Sunday, and their tiredness is likely to be a factor in how this game goes because of Sunderland's high press.
Their match against Arsenal demonstrated how incessant Regis le Bris's side are. They overpowered the Gunners, and it was incredible to watch.
Everyone talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been excellent, but Noah Sadiki, who plays in midfield with him, has also been one of the signings of the season and should be recognised too.
This promises to be this being the best game|most exciting fixture